http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108558676-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-10 |
| filingDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108558676-B |
| titleOfInvention | Preparation method of N, N-dibenzylethylenediamine diacetate |
| abstract | The invention discloses a preparation method of N, N-dibenzyl ethylenediamine diacetate, S1, adding 50 parts by weight of diacetyl dibenzyl ethylenediamine material into a three-necked bottle, and adding 80-120 parts by weight of concentrated hydrochloric acid into the three-necked bottle to obtain 36.0-37.5 parts by weight of compound B; s2, adding 200 parts by weight of water into the compound B obtained in the step S1 for full dissolution, and dropwise adding a sodium hydroxide solution to adjust the pH value to 8-9; adding toluene, extracting for many times, and carrying out layering treatment to obtain a compound C and toluene mixture organic phase; and S3, adding the organic phase of the mixture of the compound C and toluene into a three-neck flask, distilling under reduced pressure until no fraction is produced, adding ethyl acetate to dissolve the organic phase, heating to 60 ℃, dropwise adding 20 parts by weight of glacial acetic acid, and drying to obtain 47.0-49.0 parts by weight of dibenzylethylenediamine diacetate. The invention improves the safety of the reaction, reduces the reaction cost, and improves the yield of the dibenzyl ethylenediamine diacetate to more than 93 percent. |
| priorityDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.