http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108558628-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-45 |
| filingDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108558628-B |
| titleOfInvention | Preparation method of benzoin |
| abstract | A preparation method of benzoin comprises the steps of taking benzaldehyde as a raw material, a distilled water solvent, vitamin B1 as a main catalyst and hydroxypropyl beta-CD as an auxiliary catalyst, heating benzaldehyde to 50-80 ℃ in an electric heating jacket by taking water as a solvent under the catalysis of vitamin B1 and hydroxypropyl beta-CD, and carrying out condensation reaction to obtain the benzoin. The hydrogen atoms between S and N on the thiazole ring on the right side of the vitamin B1 molecule have larger acidity, and form carbanions under the action of alkali to attack the aldehyde group of benzaldehyde, so that the polarity of carbonyl carbon is reversed, the formation of benzoin is catalyzed, and the benzaldehyde is included in aqueous solution by utilizing hydroxypropyl beta-CD, so that the water solubility of the benzaldehyde is increased, the reaction of the benzaldehyde is facilitated, and the use of virulent cyanides is avoided; in addition, compared with a method which takes ethanol as a solvent and needs to be fed in an ice-water bath for preparing benzoin under the catalysis of vitamin B1, the method avoids the defects of low yield and high energy consumption caused by feeding in the ice-water bath. |
| priorityDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.