http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108543082-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-085 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
| filingDate | 2018-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e652b759964cf84d523d221cffb5bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab40f6a73e00baf0d394e7746188e8ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bb294d164be723184c62582ff5fb0d4 |
| publicationDate | 2018-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108543082-A |
| titleOfInvention | The preparation method and product of the extra small ferric oxide nano particles assembly of pH response types and application |
| abstract | The present invention relates to a kind of preparation methods of the extra small ferric oxide nano particles assembly of pH response types and product and application, preparation method to include the following steps：1) the extra small ferric oxide nano particles of Coated with Oleic Acid and the small molecule with carboxyl are subjected to ligand exchange reaction, obtain the extra small ferric oxide nano particles of carboxyl modified；2) the extra small ferric oxide nano particles of carboxyl modified carry out amidation process with the small molecule with hydrazino, obtain the extra small ferric oxide nano particles of hydrazino modification；3) the extra small ferric oxide nano particles of hydrazino modification are reacted with the compound progress aldimine condensation with more aldehyde radicals, obtain the extra small ferric oxide nano particles assembly of pH response types.The preparation method introduces hydrophilic smaller ligand, makes extra small ferric oxide nano particles chemical crosslinking at pH response type nano assemblies, it is made to have good bioavilability and imaging effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109675062-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109675062-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112007177-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109675063-A |
| priorityDate | 2018-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.