http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108543077-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-145 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108543077-B |
titleOfInvention | Mesoporous silica nanoparticle of disulfiram monomer and preparation method and application thereof |
abstract | The invention relates to a disulfiram monomer mesoporous silica nanoparticle and a preparation method and application thereof, wherein the preparation method comprises the following steps: (1) preparing mesoporous silica nanoparticles; (2) mesoporous silica nanoparticles of disulfiram monomer (diethyl dithiocarbamate) with disulfide bonds were then prepared using disulfide bonds of disulfiram. The average grain diameter of the nano-particles is 50-300nm, and the nano-particles are uniformly distributed and have good dispersibility. The mesoporous silica nanoparticle of the disulfiram monomer is beneficial to improving the targeting property of the medicament and improving the bioavailability of the medicament, has lower preparation cost of the medicament, can greatly reduce the treatment cost of patients, and has potential market value and profound social significance. |
priorityDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.