| abstract |
The invention discloses creatinine content detection reagents in a kind of human serum of anti-Calcium Dobesilate interfering effects of drug, including R1 reagents and R2 reagents, the R1 reagents include 3 N-morpholinyls, TOOS, Brij 35, gentamicin, sarcosine oxidase, kreatinase, vitamin oxidizing ferment and sulphuric acid leaching, and the R2 reagents include 3 N-morpholinyls, 4 AAP, Creatininase, Proclin300 and potassium ferrocyanide.The present invention is by preparing R1 reagents and R2 reagents, using the automatic clinical chemistry analyzer with double reagent function when use, it is measured using double reagent end-point method, ensure the accuracy of detection data, simultaneously Calcium Dobesilate interfering effects of drug is effectively eliminated by the way that sulphuric acid leaching is added in R1, the accuracy for ensureing clinical creatinine reagent detection can realize the creatinine enzyme process detection that the range of linearity is wide, anti-Calcium Dobesilate interfering effects of drug ability is strong, stability is good, accuracy is high. |