http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108530671-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2389-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-60 |
filingDate | 2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108530671-B |
titleOfInvention | Porous gelatin sponge and preparation method thereof |
abstract | The invention discloses a preparation method of porous gelatin sponge. The preparation method comprises the following steps: s1, dissolving a cross-linking agent, and adding gelatin while stirring to perform a cross-linking reaction; s2, transferring the crosslinked gelatin solution into a closed reaction container, introducing gas until the pressure in the reaction container reaches more than 1 atmosphere, and then maintaining for more than 10 min; s3, carrying out programmed cooling on the gelatin solution processed in the step S2 to completely solidify the gelatin solution; s4, freeze-drying the solidified gelatin; s5, sequentially soaking the freeze-dried gelatin in absolute ethyl alcohol and purified water to remove the cross-linking agent; s6, carrying out secondary freeze-drying and sterilization on the soaked gelatin in the step S5 to obtain the porous gelatin sponge. According to the preparation method of the porous gelatin sponge, after gelatin is crosslinked, aeration pressurization and programmed cooling solidification treatment are carried out, so that the internal porosity and the specific surface area of the gelatin sponge are effectively increased, the water absorption of the gelatin sponge is improved, the hemostasis speed of the gelatin sponge is further improved, and the hemostasis time is shortened. |
priorityDate | 2018-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.