| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2377-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-204 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3852
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L77-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 |
| filingDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108530619-B |
| titleOfInvention |
Functionalized amino acid, preparation method and functionalized amino acid hydrogel prepared from functionalized amino acid |
| abstract |
The invention relates to a functionalized amino acid, a preparation method and a functionalized amino acid hydrogel prepared from the functionalized amino acid. The preparation method comprises the following steps: s1, synthetic polyamino acid aPEG-PELG 13 (ii) a S2, synthesizing the functionalized polyamino acid aPEG-PELG-KGN. The preparation method provided by the invention can chemically connect KGN which is a small molecule to the polyamino acid to prepare the KGN-modified functional polyamino acid. The use of the above polyamino acids allows the formation of stable gels at around 33 ℃ and thus facilitates mixing with cells at low temperatures and for in vivo injection. In addition, the gel formed by adopting the functionalized polyamino acid provided by the invention has good biodegradability; the mesenchymal stem cells encapsulated in the coating can promote cell proliferation and differentiation to chondrocytes. |
| priorityDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |