http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108530365-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 |
| filingDate | 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108530365-B |
| titleOfInvention | 1, 4-naphthoquinone/anthraquinone imidazole derivative and preparation and application thereof |
| abstract | The invention discloses a1, 4-naphthoquinone/anthraquinone imidazole derivative and a preparation method and application thereof; the structural formula of the 1, 4-naphthoquinone imidazole derivative is shown as follows: or The structural formula of the 1, 4-anthraquinone imidazole derivative is shown as follows: or Wherein R is isopropyl, tert-butyl, cyclopropyl, 2-methoxyethyl, cyclohexyl, pyrazine-2-methyl, 3-methyl-2-butenyl, 2-propynyl, ethylcyano; r 1 Is H, NO 2 Or NH 2 ；R 2 、R 3 、R 6 、R 7 Respectively alkyl, alkenyl, (substituted) phenyl, heteroaryl; x 1 Is I, PF 6 、OTf、Br、Cl、MeSO 3 Or OTs; r 4 Is H, alkyl, alkenyl, (substituted) phenyl, heteroaryl; r 5 、R 8 Is H or methyl; x 2 Is Cl, Br, I, PF 6 ，OTf，OTs，OMs，ClO 4 . The derivative has novel structure, and in vitro test shows good tumor cell growth inhibition activity, and can be used for treating tumor. |
| priorityDate | 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.