http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108525007-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108525007-B |
| titleOfInvention | Keratin fiber-nerve growth factor composite scaffold for nerve tissue engineering |
| abstract | The invention discloses a keratin fiber-nerve growth factor composite scaffold for nerve tissue engineering and a preparation method thereof. The preparation method of the keratin fiber-nerve growth factor composite scaffold provided by the invention comprises the following steps: treating keratin fibers with an acidic solution to destroy the outermost epidermal layer and expose the inner cortical layer to obtain the keratin fibers after treatment; and then loading the nerve growth factor on the keratin fibers after the treatment to obtain the keratin fiber-nerve growth factor composite scaffold. The composite scaffold provided by the invention can obviously promote the survival of the neural stem cells and increase the differentiation ratio of the neural stem cells into neurons and the expression quantity of the receptor Trk A. Therefore, the NGF-keratin fiber can be used as a novel three-dimensional scaffold, and the invention provides a new method and thought for treating nervous system injury or diseases by applying a neural tissue engineering method. |
| priorityDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 158.