http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108524550-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-544 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-085 |
filingDate | 2018-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108524550-B |
titleOfInvention | Preparation method of SEB toxoid vaccine aerosol lung delivery immune mouse model |
abstract | The invention discloses a preparation method of an SEB toxoid vaccine aerosol lung delivery immune mouse model. The method for preparing the staphylococcal enterotoxin B vaccine liquid aerosol lung delivery immune animal model comprises the following steps: (1) delivering a staphylococcal enterotoxin B vaccine to the lungs of the animal by means of a liquid aerosol; (2) then delivering staphylococcal enterotoxin B to the lungs of the animals treated in step (1) by means of liquid aerosol; (3) and (3) carrying out lipopolysaccharide sensitization on the animal treated in the step (2) to obtain an animal model. The invention successfully prepares a staphylococcal enterotoxin B toxoid vaccine liquid aerosol lung delivery immune mouse model. The SEB toxoid vaccine is proved to have better immune effect after pulmonary delivery inhalation infection immunization, and can protect the SEB infection with 10 times of LD50 dose. The invention has important significance for screening staphylococcal enterotoxin B vaccines. |
priorityDate | 2018-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.