http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108524454-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-59 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59 |
filingDate | 2018-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108524454-B |
titleOfInvention | Compositions of highly dispersed low dose drugs and methods of making the same |
abstract | The invention discloses a highly dispersed low-dose drug composition and a preparation method thereof. Aims to solve the problems that the existing preparation method of the low-dose medicament can not meet the requirement of content uniformity, and especially the influence of parameter change in the amplification production process on the physicochemical property of the low-dose medicament is more obvious. The invention adopts the double screw extrusion technology to prepare the low-dose medicament for the first time, screens vitamin D structural analogue medicaments, glucocorticoid medicaments, antipsychotic medicaments, antipyretic analgesic medicaments and other low-dose medicaments as research objects, and deeply researches the preparation of the solid preparation by a double screw extruder, wherein the content uniformity of the solid preparation accords with the specification of pharmacopoeia. |
priorityDate | 2018-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.