http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108508129-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108508129-B |
| titleOfInvention | Method for measuring biological potency of heparin drugs |
| abstract | The invention provides a method for measuring the biological potency of heparin drugs, belonging to the field of biological analysis. The determination method comprises the following steps: mixing the blood coagulation factor with a to-be-detected drug, antithrombin III and a specific substrate corresponding to the blood coagulation factor to construct a potency system of the in vitro anti-coagulation factor; measuring the content of a reaction product in a titer system by a high performance liquid chromatography-mass spectrometry combined analysis method; and (3) calculating the biological potency of the drug to be detected according to a quantity reaction parallel line method by using heparin drugs with known potency as standard substances. The determination method can effectively reduce interference, has strong specificity, is simple and convenient to operate, saves time and can effectively improve the determination efficiency. |
| priorityDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.