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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P13-00
filingDate 2018-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108503534-B
titleOfInvention Extraction method and application of p-hydroxybenzoic acid
abstract The invention belongs to the technical field of microorganisms, and particularly relates to an extraction method and application of p-hydroxybenzoic acid. The method comprises the following steps: inoculating marine bacteria Arenibacter sp.6A1 into a fermentation culture medium for fermentation culture to obtain fermentation liquor; adjusting the pH value of the fermentation liquor to 3-4, and then carrying out extraction treatment to obtain an extract; dissolving the extract, and sequentially performing gel column chromatography and HPLC separation to obtain p-hydroxybenzoic acid; wherein the conditions for HPLC separation comprise: gradient eluting with methanol/water mixed solvent, detecting wavelength of 254nm, and collecting liquid phase peak for 25 min. The method finally obtains the hydroxybenzoic acid with high purity and algae-dissolving activity, and provides a good foundation for the industrial production of the hydroxybenzoic acid.
priorityDate 2018-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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