abstract |
The present invention relates to Pharmacological inhibitors technical fields, and in particular to a kind of 1 tumour immunity inhibitor of novel PD and its process for preparing medicine, the immunosuppressor are made of following parts by weight raw material:30 45 parts of 1 monoclonal antibodies of PD, 26 parts of alkaloids, 47 parts of antibiotic, 39 parts of alkylating agents, 15 parts of platinum agent, 59 parts of metabolic antagonist compositions;Wherein, alkaloid is made of one or more in taxol, vincristine, Taxotere;Antibiotic is made of one or more in epirubicin, idarubicin, mitomycin;Alkylating agent is one or both of ifosfamide, Dacarbazine;Platinum agent is one or both of cis-platinum, oxaliplatin;Metabolic antagonist is one or more in gemcitabine, cytarabine, Tegafur;Immunosuppressor provided by the present invention can block the interaction of the PD L1 molecules and the receptor on activating T cell expressed on tumour cell, and inhibit the apoptosis of activating T cell, improve the killing ability to tumour cell. |