http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108490178-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-62 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108490178-B |
titleOfInvention | Markers for NPC diagnosis and prognosis prediction and their applications |
abstract | The invention discloses markers for NPC diagnosis and prognosis prediction and their applications. The inventors used ELISA method to detect the concentration of INSL5 in the sample plasma, and found that the plasma concentration of INSL5 was significantly different between the two groups of nasopharyngeal cancer patients and healthy people. The ROC curve analysis showed that the area under the curve of INSL5 was 0.941, and the The critical value of the concentration was 2.45ng/ml, and its sensitivity and specificity were 93.2% and 81.5%, respectively. In the healthy population group, the concentration of INSL5 in EBV-positive plasma was significantly higher than that in EBV-negative plasma samples. In all EBV-negative populations, there were 34 healthy people and 72 nasopharyngeal carcinoma patients, and there was still a statistically significant difference in the concentration of INSL5 between the two groups. The ROC curve results showed that the area under the INSL5 curve was 0.988. The critical value of INSL5 concentration was 2.25ng/ml, and its sensitivity and specificity were 97.2% and 91.2%, respectively, which could well distinguish EBV-negative normal people from NPC patients. |
priorityDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.