http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108486173-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-50 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-50 |
filingDate | 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108486173-B |
titleOfInvention | Preparation method of alpha-ketoglutaric acid |
abstract | The invention relates to a preparation method of alpha-ketoglutaric acid, belonging to the technical field of biological engineering 660nm Growing to 10-20, adding lactose into the fermentation medium, continuing induction culture, and centrifugally collecting wet thalli; forming a conversion system by using L-glutamic acid or L-glutamate, manganese sulfate, catalase and wet bacteria, adjusting the pH value of the conversion system to be 4-8, and converting for 20-30h under the conditions of temperature of 20-40 ℃, rotation speed of 100-400rpm and air volume of 10-25L/min to obtain a conversion solution; the extraction is to obtain the alpha-ketoglutaric acid by filtering, purifying, decoloring, concentrating and crystallizing the conversion solution. The invention mainly optimizes fermentation and conversion conditions, shortens production period, improves yield and yield of alpha-ketoglutaric acid, and is suitable for industrial large-scale production. |
priorityDate | 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 202.