http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484795-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0069
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737
filingDate 2018-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108484795-B
titleOfInvention Lithium chondroitin sulfate and preparation method and application thereof
abstract The present invention provides lithium chondroitin sulfate andthe preparation method and the application of the compound are that the chondroitin sulfate lithium is a polysaccharide with a novel chemical structure and has potential double anti-AD effects of the chondroitin sulfate and lithium salt. The lithium salt has certain cytotoxicity, and the invention replaces lithium on chondroitin sulfate to prepare the lithium chondroitin sulfate, so that the lithium chondroitin sulfate is basically free from cytotoxicity, has better effect of interfering and inhibiting A beta aggregation than sodium chondroitin sulfate, and can reduce A beta induced neurotoxicity. Lithium chondroitin sulfate on Abeta 25‑35 The prevention and protection effect of inducing nerve cell damage is far better than that of sodium chondroitin sulfate.
priorityDate 2018-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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