http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484795-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0069 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 |
filingDate | 2018-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108484795-B |
titleOfInvention | Lithium chondroitin sulfate and preparation method and application thereof |
abstract | The present invention provides lithium chondroitin sulfate andthe preparation method and the application of the compound are that the chondroitin sulfate lithium is a polysaccharide with a novel chemical structure and has potential double anti-AD effects of the chondroitin sulfate and lithium salt. The lithium salt has certain cytotoxicity, and the invention replaces lithium on chondroitin sulfate to prepare the lithium chondroitin sulfate, so that the lithium chondroitin sulfate is basically free from cytotoxicity, has better effect of interfering and inhibiting A beta aggregation than sodium chondroitin sulfate, and can reduce A beta induced neurotoxicity. Lithium chondroitin sulfate on Abeta 25‑35 The prevention and protection effect of inducing nerve cell damage is far better than that of sodium chondroitin sulfate. |
priorityDate | 2018-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.