http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484635-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108484635-B |
titleOfInvention | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof |
abstract | The invention belongs to the technical field of medicines, and relates to 4H-thieno [2,3-b ]]Thiopyran-4-ketone compounds, a preparation method thereof and application thereof as epidermal growth factor receptor tyrosine kinase inhibitors. The invention provides compounds, prodrugs and pharmaceutically active metabolites thereof, and pharmaceutically acceptable salts thereof, having the structural formula: wherein, R can be independently selected from hydrogen, halogen, hydroxyl, nitro, cyano, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkyl substituted by halogen atoms and C1-C4 alkoxy substituted by halogen atoms. |
priorityDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.