| abstract |
The invention discloses the preparation methods of a kind of aryl substituted pyrazolecarboxylic and its derivative.Preparation method proposed by the present invention using substituted phenylethylene and diazonium compound be raw material, oxygen or air as oxidant, alkali as additive, add suitable solvent and dehydrating agent, reacted under initiation temperature, then through cooling, be filtered, washed, extract, dry, filter, depressurize boil off organic phase solvent, column chromatography for separation obtains aryl substituted pyrazole compounds and its derivativeļ¼It is raw material one pot process 5 aryl substituted pyrazolecarboxylics and its derivative from substituted phenylethylene and diazonium compound to realize directly. |