http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108479738-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-286 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286 |
filingDate | 2018-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108479738-B |
titleOfInvention | Hydrophobic chromatography medium, preparation method and application thereof |
abstract | The invention provides a hydrophobic chromatography medium, a preparation method and application thereof, belonging to the technical field of protein chromatographic separation in the field of biochemical engineering. The 1-naphthylacetic acid is immobilized on a hydrophilic gel carrier to prepare a novel hydrophobic chromatography medium for separating and purifying proteins. Compared with the conventional hydrophobic chromatography medium, the hydrophobic medium prepared by adopting 1-naphthylacetic acid as the immobilized ligand can realize protein adsorption and elution regulated by pH under the condition of low salt concentration, and has the characteristic of high loading capacity. By adjusting the pH value of the buffer solution, the adsorption and desorption of proteins such as lysozyme, antibody and the like can be respectively realized. |
priorityDate | 2018-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.