http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108478871-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40 |
filingDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108478871-B |
titleOfInvention | Integrated bone-cartilage repair scaffold and preparation method thereof |
abstract | The invention provides an integrated bone-cartilage repair support which is an integrated structure consisting of a subchondral bone repair layer, an intermediate layer and a cartilage repair layer, wherein the subchondral bone repair layer is formed porous calcium phosphate bioceramic, the intermediate layer is sulfydryl-hyaluronic acid hydrogel, the cartilage repair layer consists of I-type collagen hydrogel and chondrocytes or mesenchymal stem cells, and the intermediate layer is positioned between the subchondral bone repair layer and the cartilage repair layer and in the porous structure of the formed porous calcium phosphate bioceramic and separates the subchondral bone repair layer from the cartilage repair layer. The invention also provides a preparation method of the integrated bone-cartilage repair scaffold. The repair scaffold provided by the invention can prevent blood vessels from invading the cartilage layer, improve the connection tightness and stability between the bone layer and the cartilage layer, realize biological combination of the bone layer and the cartilage layer and achieve good repair effect. |
priorityDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.