http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108478853-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 |
| filingDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108478853-B |
| titleOfInvention | Composite hydrogel and preparation method and application thereof |
| abstract | The invention relates to a composite hydrogel and a preparation method and application thereof, wherein the hydrogel is formed by chemically crosslinking polylysine and graphene oxide, the molecular weight of the polylysine is 3000-5000 Da, and the mass ratio of the graphene oxide to the polylysine is 0.01: 1-1: 1. The preparation method of the hydrogel comprises the following steps: s1: adding water to polylysine for dissolving, sequentially adding a cross-linking agent and graphene oxide, and stirring under a sealed condition; s2: dialyzing the solution obtained in S1, pouring the solution in the dialysis bag into a mold, and irradiating under sealed condition. The composite hydrogel provided by the invention takes polylysine as a raw material, has good biocompatibility and no irritation to tissues, and can improve local microenvironment of a wound surface, accelerate wound healing and prevent infection. Meanwhile, the preparation method of the composite hydrogel provided by the invention is simple, and the obtained composite hydrogel has high mechanical strength. |
| priorityDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.