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filingDate 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108478588-B
titleOfInvention Tilmicosin slow-release enteric solvent and preparation method thereof
abstract The invention relates to the field of veterinary drugs, and in particular relates to a tilmicosin slow-release enteric solvent and a preparation method thereof. The tilmicosin slow-release enteric solvent comprises the following components in parts by weight: 20-25 parts of tilmicosin, 1-3 parts of povidone and 65-80 parts of carrier; the carrier is selected from one or more of flour, corn starch, microcrystalline cellulose, sodium carboxymethyl starch and hydroxypropyl methyl cellulose. According to the invention, by improving the formula and preparation process of the tilmicosin slow-release enteric solvent and adopting an extrusion and spheronization technology to prepare the tilmicosin slow-release enteric solvent, the coating rate is more than 99.99%, the bitter taste of tilmicosin can be almost completely covered, gastric acid reaching the stomach does not overflow, the tilmicosin slow-release enteric solvent is released in the intestinal tract after being eaten by pigs, the retention time of the tilmicosin in the intestinal tract is prolonged to play a slow-release role, and the phenomenon of regurgitation and vomiting after the pigs are only eaten by pigs is avoided.
priorityDate 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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