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filingDate 2018-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108478540-B
titleOfInvention Preparation method of tripterygium wilfordii slow-release microcapsule
abstract The invention discloses a preparation method of tripterygium wilfordii slow-release microcapsules, which comprises the steps of adopting ultrasonic wave to cooperate with supercritical CO 2 Extracting and separating by high pressure liquid chromatography to purify triptolide extract with purity of about 95% to make its purity reach more than 99%; then preparing the triptolide purified extract with the purity of more than 99 percent into the sustained-release microcapsule. The invention reduces the influence of impurities on triptolide extract in drug treatment, and is beneficial to researchers to take effective measures to treat the toxicity of the triptolide extract in a targeted manner; the invention carries out microencapsulation treatment on the purified triptolide extract, has high embedding property and good slow release speed of the medicine, can slowly release the active ingredients in the medicine, prolongs the release, absorption and distribution of the medicine in vivo, and thus reduces the toxicity of the triptolide to human bodies.
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