abstract |
The invention relates to fused heteroaryl-substituted 1,2,4-triazine-3-amine derivatives, a preparation method thereof and its application in medicine. Specifically, the present invention relates to a fused heteroaryl-substituted 1,2,4-triazine-3-amine derivative represented by general formula (IM), a preparation method thereof and a pharmaceutical composition containing the derivative and its use as a therapeutic agent, especially as an A2a receptor antagonist and in the preparation of a medicament for the treatment of a condition or disorder improved by inhibition of the A2a receptor, wherein the general formula (IM) Each substituent of is the same as defined in the specification. |