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filingDate 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108456192-B
titleOfInvention Two-photon fluorescent sodium ion probe and synthetic method and application thereof
abstract The invention belongs to the technical field of fine chemical engineering, and particularly relates to a two-photon fluorescent sodium ion probe, a synthesis method and application thereof. The probe has small molecular volume and good selectivity on sodium ions, and other ions except the sodium ions such as zinc, potassium, calcium, magnesium, manganese, mercury and the like do not interfere with detection, so that the sodium ions with micromolar concentration can be detected. The fluorescence intensity of the probe molecules is reduced after complexing sodium ions, and two-photon fluorescence detection can be performed on the content of the sodium ions. The two-photon fluorescence microscopic imaging experiment shows that the probe has good permeability to cells or tissues such as fibroblasts and the like, has no toxic or side effect on the cells, is particularly suitable for detecting the concentration change of sodium ions in the cells and the distribution of mercury ions, and has great application value in the fields of biology and medicine.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109946276-A
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type http://data.epo.org/linked-data/def/patent/Publication

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