http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108456192-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
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filingDate 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57575dbb480e4489bef33fb2095d5388
publicationDate 2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108456192-A
titleOfInvention Two-photon fluorescence sodium ion probe and its synthetic method and application
abstract The invention belongs to technical field of fine, and in particular to a kind of two-photon fluorescence sodium ion probe and its synthetic method and application, the probe are prepared by two-photon fluorescence parent of dicyanogen methyl isophorone stilbenes.The probe molecule is small, has good selectivity to sodium ion, and other ion pairs detection other than the sodium ions such as zinc, potassium, calcium, magnesium, manganese, mercury does not interfere with, and can detect the sodium ion of micro-molar concentration.Fluorescence intensity declines after sodium ion is complexed in probe molecule, can carry out two-photon fluorescence detection to sodium ions content.The experiment of two-photon fluorescence micro-imaging shows this kind of probe to the cell or tissues good penetrability such as fibroblast, itself there is no toxic side effect to cell, particularly suitable for the detection of the variation of intracellular Na ion concentration and mercury ion distribution, there is great application value in biology, field of medicaments.
priorityDate 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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