http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108456157-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C337-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C337-06 |
| filingDate | 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108456157-B |
| titleOfInvention | 1-substituted benzoyl-4-fatty acyl semicarbazide derivatives, preparation method and application as antibacterial drugs |
| abstract | The invention belongs to the technical field of antibacterial drugs, and relates to a 1-substituted benzoyl-4-fatty acyl semicarbazide derivative, a preparation method and application thereof as an antibacterial drug. The compound is shown as a formula (I), wherein R 1 Selected from hydrogen, hydroxy, C1-C3 alkyl, C1-C8 alkyloxy, C3-C6 cycloalkyloxy, C3-C6 cycloalkylmethoxy, unsubstituted or halogenated phenyl C1-C3 alkoxy, phenyl, C1-C3 alkylbenzene, halogenated benzene, R 1 The substitution position of (A) is selected from ortho-, meta-or para-position；R 2 Selected from the group consisting of unsubstituted or halogenated C1-C8 alkyl, unsubstituted or halogenated C3-C6 cycloalkyl, unsubstituted or halogenated phenyl C1-C3 alkyl; x is selected from sulfur or oxygen. The 1-substituted benzoyl-4-fatty acyl semicarbazide derivative has a strong inhibition effect on gram-positive bacteria, particularly drug-resistant bacteria such as methicillin-resistant staphylococcus aureus (MRSA), methicillin-resistant staphylococcus epidermidis (MRSE) and vancomycin-resistant enterococci (VRE), and can be used for preparing novel drug-resistant bacteria drugs. |
| priorityDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.