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filingDate 2018-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108445236-B
titleOfInvention Steroid derivative, preservation solution thereof and application thereof
abstract The invention discloses a steroid derivative, a preservation solution and application thereof, and belongs to the technical field of in-vitro diagnostic reagents. The steroid derivative contains a cyclopentane multi-hydrogen phenanthrene mother nucleus, and at least one carbon position of the cyclopentane multi-hydrogen phenanthrene mother nucleus is substituted with a hydrophilic group. The preservation solution of the steroid hormone comprises a buffer solution and a surfactant dissolved in the buffer solution. The steroid derivative and the preservation solution are applied to preparation of a detection agent and a kit for detecting steroid hormones. The steroid derivative has good hydrophilicity and solubility, can be uniformly and stably dispersed in a solution, is used as a steroid hormone antigen, and can realize accurate detection of steroid hormone. The steroid hormone preserving fluid can effectively improve the solubility and the dispersion uniformity of the steroid derivatives and prevent the steroid derivatives from being adsorbed on the surface of a high molecular polymer.
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