http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108445213-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
filingDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108445213-B
titleOfInvention Nano composite probe, composition and fluorescent quantitative kit for high-sensitivity fluorescent quantitative detection of serum tumor marker
abstract The invention relates to the field of fluorescent quantitative detection, and provides a nano composite probe for high-sensitivity fluorescent quantitative detection of a serum tumor marker. The nano composite probe provided by the invention takes gold nanoparticles as a carrier, and carries the deoxyribozyme with high catalytic property, so that the formed composite not only retains the high catalytic property and the recognition capability of the deoxyribozyme, but also introduces the signal transduction function of a nano material, and realizes the integration of the recognition and the signal transduction function. The sensitivity and specificity of fluorescent quantitative detection are obviously improved by combining the efficient specificity recognition function of a tumor marker, the high recognition and catalytic property combination of deoxyribozymes and the signal transduction and fluorescence amplification functions of gold nanoparticles, and the detection sensitivity can reach 0.01 ng/mL.
priorityDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.