http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108445113-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02
filingDate 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108445113-B
titleOfInvention On-line solid-phase extraction liquid chromatography analysis method for the detection of clonazepam in blood
abstract The on-line solid-phase extraction liquid chromatography analysis method for detecting the content of clonazepam in blood of the present invention is to use a high performance liquid chromatograph and a DVD detector to calibrate the standard solution, and the equation of the standard curve obtained by fitting is y=a*x+ b. Take the blood sample to be tested. After the blood to be tested is processed, the sample to be tested is also detected by high performance liquid chromatography and DVD detector to obtain the blood y value to be tested. Substitute the blood y to be tested into the standard curve In the equation, the relative concentration x of clonazepam in the blood sample to be tested is obtained by calculation, and the concentration of the working solution of the internal standard is known, so the drug concentration of clonazepam in the blood to be tested in the sample is calculated, and this According to the invention, the serum is directly injected into the sample after precipitation and centrifugation, so that the detection process is simple and fast, the experiment cost is reduced, and the blood concentration of clonazepam in the patient's body can be monitored in clinical treatment.
priorityDate 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.