http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108440542-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d890ad239375a780e6827d3407f15ef3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
| filingDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_349f53d408f6db3d16547d142bcda8f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e29b1fc2eb20478c1fb4e02bceed490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5852971bede56e3b9d2a74b19c56ab9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da35a7e35fc5021145c9b47e86d64368 |
| publicationDate | 2018-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108440542-A |
| titleOfInvention | A kind of preparation method with optical activation for adjoining double loop coil oxidized indole compounds |
| abstract | Disclosed in the present application is a kind of preparation method with optical activation for adjoining double loop coil oxidized indole compounds in organic synthesis field,By by chiral lewis base,MBH carbonic esters derived from isatin and 3 carbonyl alkenyl benzo-heterocycle compounds are dissolved in organic solvent,Under the catalysis of chiral lewis base,Asymmetric [3+2] cycloaddition reaction occurs for MBH carbonic esters derived from isatin and 3 carbonyl alkenyl benzo-heterocycle compounds,It generates and adjoins double loop coil oxidized indole compounds with optical purity high (high dr and ee),The simple column chromatography of product or chromatography separation,I.e. separable acquisition is with optical activation to adjoin double loop coil oxidized indole compounds,This method reaction condition is mild,Proper temperature,It is easy to operate,Equipment is simple,The optical purity of preparation-obtained chipal compounds is high. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111892608-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111892608-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111961060-A |
| priorityDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.