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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48
filingDate 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108440383-B
titleOfInvention Preparation method of rivaroxaban intermediate
abstract The invention relates to a preparation method of rivaroxaban intermediate S-N-glycidol phthalimide. The method uses the alumina which can be recycled repeatedly for catalytic reaction in the preparation process of the S-N-glycidylphthalimide, reduces the production cost, reduces the emission requirement, solves the problem that the phase transfer catalyst is difficult to remove and influences the product quality, further shortens the reaction time, avoids the special requirement on equipment caused by the use of potassium tert-butoxide, reduces the production cost, and is particularly suitable for industrial production.
priorityDate 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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