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filingDate 2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108440368-B
titleOfInvention A kind of fluorescence probe and its preparation method and application with AIE effect
abstract The invention belongs to fluorescence probe field more particularly to a kind of fluorescence probes and its preparation method and application with AIE effect.The present invention provides a kind of fluorescence probes with AIE effect, the experimental results showed that this has the fluorescence probe of AIE effect can be with Sensitive Detection biology thiol molecule, there is strong fluorescence response to cysteine (Cys) and homocysteine (Hcy), but to glutathione (GSH) without response, solve the problems, such as that GSH, Cys and Hcy are because the similitude of its structure is often difficult to be distinguished with existing fluorescence probe in biological sulfhydryl compound.Also, there is the present invention fluorescence probe of AIE effect to be able to solve the ACQ effect that probe is generated by poorly water-soluble.
priorityDate 2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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