http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108409738-A

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filingDate 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_428095b383532caa7aacdbb5166c32b1
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publicationDate 2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108409738-A
titleOfInvention 3,4-methylenedioxyphenyl substituted tetrahydro-β-carboline piperazine diketone derivatives and uses thereof
abstract The invention relates to a 3,4-methylenedioxyphenyl substituted tetrahydro-β-carboline piperazine diketone derivative and its application. Specifically, the present invention discloses a compound represented by formula I or its stereoisomer, or a pharmaceutically acceptable salt thereof, and the definition of each group is detailed in the description. The compound of the present invention has dual inhibitory activities of acetylcholinesterase and phosphodiesterase 5, and has good blood-brain barrier permeability. Therefore, the compound of the present invention can be used in the preparation of drugs for treating and/or preventing Alzheimer's disease.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111269220-A
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priorityDate 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 35.