http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108409587-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80fdaa0d94f29478467816f48d47639e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-60 |
| filingDate | 2017-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be20f0f2cd2cfe19a93a631f8c6ee8b |
| publicationDate | 2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108409587-A |
| titleOfInvention | A kind of synthetic method of pharmaceutical intermediate gavaculine |
| abstract | A kind of synthetic method of pharmaceutical intermediate gavaculine, mainly includes the following steps：The stannous chloride of 3mol, the toluene solution of 4-5mol, the m-Nitrobenzoic Acid solution of 5mol are added in the reaction vessel, solution temperature is increased to 60-70 DEG C, controls 110-130rpm of mixing speed, keeps 90-110min, pH value of solution is adjusted to 9 10 with sodium hydroxide solution, is reduced solution temperature to 5-10 DEG C, is precipitated crystal, the washing of 6L ethanol solutions is added, sodium chloride solution washs, nitromethane solution washing, ethylenediamine solution washing, dehydrating agent is dehydrated, and obtains finished product gavaculine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112358409-A |
| priorityDate | 2017-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.