http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108404216-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-10 |
filingDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108404216-B |
titleOfInvention | A kind of gradient composite material and its preparation method and application |
abstract | The present invention relates to a gradient composite material and its preparation method and application. The method includes: using an organic solvent to formulate a biocompatible polymer and a bioactive ceramic powder into multiple slurries with different contents of the bioactive ceramic powder; Layer-by-layer casting or layer-casting co-pressing in a descending manner produces a gradient composite material comprising a multi-layer cast film. The gradient composite material preferably contains 4 layers of casting film, from the first layer of casting film to the fourth layer of casting film, the volume percentage of the bioactive ceramic powder is 0%, 30%, 50% and 70% in turn. . The gradient composite material prepared by the invention can promote the early adhesion and proliferation of osteoblasts and fibroblasts, effectively promote the formation of the transition layer between tendon and bone tissue, and the tendon-bone bonding strength can be increased by 38.6%; Gradient composites can be used as tendon-bone healing patch materials, which are potential biomedical materials. |
priorityDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.