abstract |
The invention discloses a kind of Plerixafor injections, are made of Plerixafor, acetic acid, natrium adetate, propylene glycol and water for injection.The present invention uses cosolvent of the acetic acid as Plerixafor, and adds the polarity of propylene glycol adjustment solvent to improve Plerixafor solubility, to solve the problems, such as that Plerixafor injection easily crystallizes.Injection provided by the invention, quality stability is good, and Clinical practice safety, quality grinds commercial preparation better than original. |