http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108395378-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80fdaa0d94f29478467816f48d47639e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C223-06 |
| filingDate | 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be20f0f2cd2cfe19a93a631f8c6ee8b |
| publicationDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108395378-A |
| titleOfInvention | A kind of synthetic method of pharmaceutical intermediate o-Aminobenzaldehyde |
| abstract | A kind of synthetic method of pharmaceutical intermediate o-Aminobenzaldehyde, mainly includes the following steps：The o-nitrobenzaldehyde of 2mol is added in the reaction vessel, 50L water, the stannous chloride of 3 4mol, 2 amino toluenes of 5 6mol, 90-130rpm of control mixing speed, solution temperature is increased to 70-75 DEG C, 70-90min are reacted, 80-86 DEG C of fraction is collected in vacuum distillation, collect distillate, the potassium bromide of 1 2kg is added, reduces solution temperature to 5-8 DEG C, precipitates crystal, filtering, it is washed with dimethylamine solution, is washed with trifluoroacetic acid solution, dehydrating agent dehydration, it is recrystallized in ethane solution, obtains finished product. |
| priorityDate | 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.