| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcaa03b795cd8da869d58e8f28bf52e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_157f6ea8a2b996328769d9b5e934655f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 |
| filingDate |
2017-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8639dc6bc3e88828f0c5d6bc65fa3b67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b21775a63d2b4e8d64aedd97c9d1216f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad69032862659a0c9dcca9ed91947b4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b598a2d2114b6139a14485c7e9c36a5e |
| publicationDate |
2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108384819-A |
| titleOfInvention |
A kind of culture medium and fermentation method for fermenting tacrolimus |
| abstract |
The invention discloses a culture medium and a fermentation method for fermenting tacrolimus. The medium includes a carbon source and a nitrogen source, wherein the carbon source includes soluble starch 30-70g/L, fructose 5-20g/L and lactose 5-20g/L, and the nitrogen source includes fish meal peptone 1-40g /L and yeast extract 10‑30g/L. The yield of tacrolimus fermented by the culture medium or the fermentation method of the present invention is high, and the titer is three times of that of the existing culture medium, reaching more than 1000 mg/L. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109735467-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112111482-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109735467-B |
| priorityDate |
2017-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |