http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108383799-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b63eecd60f32153abcb6478d3930dc3a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2017-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296aa3baffe3b1b169c9ad3858e9796d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df60315505a3146e285119620e83e097 |
| publicationDate | 2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108383799-A |
| titleOfInvention | The synthetic method and its pharmaceutical salts and solid pharmaceutical preparation of anti-cancer agent |
| abstract | A kind of synthetic method of antineoplastic of disclosure of the invention, chemical name are 5 chlorine N2 (3 glycyl aminophenyl) N4 (2 isopropyl sulfuryl phenyl) pyrimidine 2,4 diamines.Meanwhile its salt form, crystal form are studied, filter out the maleate for being suitble to be further used as formulation development, tartrate and succinate and its corresponding crystal form.The present invention also provides more than one to state the solid pharmaceutical preparation that antineoplastic is active constituent, wherein being added with one or more acidizers.The dissolving out capability and excellent in stability of solid pharmaceutical preparation of the present invention have potential applicability in clinical practice. |
| priorityDate | 2017-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.