http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108383783-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_372338508c8646c4a6e59b6be42ccb56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 |
| filingDate | 2017-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64e1fd3310c6423603536939483374f0 |
| publicationDate | 2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108383783-A |
| titleOfInvention | The synthetic method of 4,6- dihydroxy quinoline -5,8- diquinone -2- formic acid pharmaceutical intermediates |
| abstract | The invention discloses the synthetic methods of 4,65,8 diquinone of dihydroxy quinoline, 2 formic acid pharmaceutical intermediate, include the following steps：4,65,8 dimethoxy-quinoline of dihydroxy, 2 formic acid is added in the reaction vessel, octane solution increases temperature, and potassium persulfate is being added in batches, is controlling mixing speed, aqueous solution is being added, the reaction was continued；Nitric acid cadmium dust is added in batches, increases solution temperature, potassium sulfate solution is added, the reaction was continued, reduces temperature, stands, solution is layered, it is multiple that sodium chloride solution washing is added, the washing of methyl ether solution is multiple, is recrystallized in ortho-chlorotolu'ene solution, dehydrating agent is dehydrated, obtain 4,65,8 diquinone of dihydroxy quinoline of finished product, 2 formic acid. |
| priorityDate | 2017-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.