http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108383703-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-80 |
| filingDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108383703-B |
| titleOfInvention | 3' -chlorophenylpropanol synthesis process |
| abstract | The invention relates to a 3 '-chlorobenzene propanol synthesis process, which comprises the following steps of sequentially adding 3' -chlorobenzene acetone and levorotatory prolinol into 95% ethanol and stirring; cooling after the reaction liquid is completely dissolved; adding potassium borohydride into the reaction solution in batches, and preserving heat after adding; heating the reaction solution for reflux reaction, and concentrating the reaction solution under reduced pressure; adding n-hexane into the reaction solution, heating, and adding active carbon for heat preservation and decoloration; filtering the reaction solution, leaching a filter cake by using normal hexane, and collecting filtrate; crystallizing and filtering the filtrate, leaching the filter cake once with n-hexane, and drying in vacuum to obtain 3' -chlorophenylpropanol; according to the invention, 3' -chloropropiophenone is used as a main raw material, 95% ethanol is used as a solvent, potassium borohydride is used as a reducing agent, and levorotatory prolinol is used as a catalyst to synthesize the final product dextrorotatory 3' -chloropropiophenone, the 3' -chloropropiophenone produced by the invention is used as a dextrorotatory product, the crystallization temperature is higher than that of a mixed rotation product, a special cooling device is not needed to achieve the purpose, the energy consumption is reduced, and the cost is saved. |
| priorityDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.