http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108379666-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 |
| filingDate | 2018-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108379666-B |
| titleOfInvention | Gelatin microsphere/magnesium phosphate based bone cement drug sustained-release carrier and preparation method thereof |
| abstract | The invention discloses a gelatin microsphere/magnesium phosphate based bone cement drug sustained-release carrier and a preparation method thereof, wherein 1-ethyl- (3-dimethylaminopropyl) carbodiimide hydrochloride cross-linked drug-loaded gelatin microsphere is prepared; and uniformly mixing the obtained drug-loaded gelatin microspheres with magnesium phosphate-based bone cement powder, and blending and curing the mixture with magnesium phosphate-based bone cement liquid to obtain the gelatin microsphere/magnesium phosphate-based bone cement drug sustained-release carrier. 1-ethyl- (3-dimethylaminopropyl) carbodiimide hydrochloride is used as a gelatin crosslinking agent, and the obtained gelatin microsphere has good biocompatibility; the gelatin microspheres can carry various drugs, and the degradation speed of the microspheres can be controlled by the concentration of the cross-linking agent, so that the drug release speed is controlled; the gelatin microsphere/magnesium phosphate based bone cement drug carrier has excellent drug slow release effect, and realizes the sustained release of the drug for several months. |
| priorityDate | 2018-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.