http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108374027-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 |
filingDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108374027-B |
titleOfInvention | A kind of preparation method of R-3- aminobutyric acid |
abstract | The invention discloses a kind of preparation methods of R-3- aminobutyric acid, this method is using crotonic acid, ammonium salt as substrate, the salt containing magnesium ion is added, pH is adjusted with ammonium hydroxide, then recombinant aspartic enzyme is added as biological enzyme agent, it is reacted under preference temperature and alkaline condition, through separation, purifying, crystallization after reaction, obtains R-3- aminobutyric acid.This method controls back reaction and reduces the generation of by-product by the ammonium ion of control reaction system;The quality product of high chiral purity and high impurity purity is obtained by continuous condensing crystallizing using the impurity such as micro-filtration and nanofiltration retention bacterium mud, zymoprotein, sulfate ion and pigment. |
priorityDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.