http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108373482-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108373482-B |
| titleOfInvention | A kind of preparation method of 3- alkynyl isocoumarin class compound |
| abstract | The invention discloses the synthetic methods of 3- alkynyl isocoumarin class compound, it is with 2- (2,2- dibromo vinyl) benzoic acid derivative and terminal alkyne compound be raw material, using divalent palladium and monovalence copper as catalyst, triaryl phosphine compound and alkali are additive, heating reaction in organic solvent, synthesizes a series of 3- alkynyl isocoumarin class compounds.Chemical equation is as follows: This method is simple with step, mild condition, the reaction time is short, Atom economy is high, raw material is easy to get, advantages of environment protection.Since 3- alkynyl isocoumarin class compound is a kind of important bioactive molecule and synthetic intermediate, has a very wide range of applications in pharmaceutical synthesis field, there is biggish use value and social benefit. |
| priorityDate | 2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.