| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d42f684941d5b0617ca7764ebdff07 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70592
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-149 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-537
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2016-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21332eff31e0aa7281ed22e41720b635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97518844d9289e0c092763a046c0bf7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b953fd1755ded2751d3a4ff7d4d86fee |
| publicationDate |
2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108368504-A |
| titleOfInvention |
Early post-transfection isolation (EPIC) of cells for biologics production |
| abstract |
Provided herein are methods for selecting a population of cells expressing a target polypeptide. In some aspects, the present disclosure provides for early expression of selectable polypeptides based on populations of transfected host cells for use in sorting and selection methods. In certain embodiments, sorting is performed using fluorescence-activated cell sorting or magnetic-activated cell sorting based on the selectable polypeptide. Such selection methods can further be used to generate clonal populations of producer cells, eg, for large-scale manufacturing of a target polypeptide of interest. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110050065-A |
| priorityDate |
2015-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |