| abstract |
The present invention includes novel compounds and methods for preventing or treating diseases associated with and/or caused by overexpression and/or uncontrolled activation of tyrosine kinases in a subject in need thereof. In certain embodiments, compounds of the invention include tyrosine kinase inhibitors, linkers, and ubiquitin ligase conjugates. The methods of the invention comprise administering to said subject a pharmaceutically effective amount of at least one compound of the invention. |