http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108358945-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-47 |
| filingDate | 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108358945-B |
| titleOfInvention | Method for simultaneously preparing high-purity carnosol and carnosic acid from rosemary extract |
| abstract | A method for simultaneously preparing high purity carnosol and carnosic acid from rosemary extract is provided. Dissolving herba Rosmarini officinalis extract with water saturated ethyl acetate; mixing the dissolved normal phase silica gel sample, loading the sample on a column by a dry method, performing gradient elution by using chloroform, methanol and acetic acid (100-95) to (0-5) to (0-1 thousandth), combining the same components, and performing reduced pressure concentration to obtain carnosol with the purity of about 85 percent and crude carnosic acid with the purity of about 90 percent; and respectively purifying by Sephadex LH-20 gel column chromatography, eluting with chloroform-methanol or petroleum ether-chloroform-methanol, mixing the same components, and evaporating under reduced pressure to obtain carnosol and carnosic acid with purity of over 98%. The method can simultaneously obtain high purity carnosol and carnosic acid with content of 98% or more from herba Rosmarini officinalis extract. The gel column can be used repeatedly, and has short column chromatography time and high efficiency. The method is simple, easy to operate, high in yield and suitable for large-scale production. |
| priorityDate | 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.