http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108358841-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108358841-B |
| titleOfInvention | 4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivatives, and preparation method and application thereof |
| abstract | A4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivative and a preparation method and application thereof relate to an N' -substituted methylene-4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivative. The N' -substituted methylene-4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivative can be applied to preparation of antitumor drugs. Provides a novel derivative for stimulating Nur77 signal channel, which can block tumor cell proliferation and induce apoptosis by stimulating Nur77 related signal channel activity, thereby being used for treating and preventing various diseases of human and animals such as malignant tumor, inflammation and the like. The derivative for stimulating the Nur77 signal channel can be applied to the preparation of various medicaments for treating diseases of human and animals, wherein the diseases comprise malignant tumors, inflammations and the like. |
| priorityDate | 2018-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.